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yfiR [2019-09-02 11:36:48]
transcriptional regulator ([SW|TetR family]) of the [gene|09D56215645F3E13803704F96FC6AD3FAAD58EF4|yfiS]-[gene|search|yfiR ]operon
function
control of [gene|search|yfiS ]expression
product
transcriptional regulator ([SW|TetR family])
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.6|Transcription factor/ other/ based on similarity]Gene
Coordinates
911,964 912,581
The protein
Protein family
[SW|TetR family][SW|Domains]
[SW|HTH tetR-type domain] (aa 11-71) (according to UniProt)Structure
[PDB|1RKT] [Pubmed|16862575]Expression and Regulation
Operons
genes
[gene|09D56215645F3E13803704F96FC6AD3FAAD58EF4|yfiS]-[gene|15DE8BAFB36296B5842E283C836D600755786397|yfiR]
description
(according to [http://dbtbs.hgc.jp/COG/prom/yfiSR.html DBTBS]) null
regulatory mechanism
[protein|857EF1AC54DEA0690C01B7F8CEFFD16312C58F20|TnrA]: activation, [Pubmed|25755103], in [regulon|857EF1AC54DEA0690C01B7F8CEFFD16312C58F20|TnrA regulon][protein|15DE8BAFB36296B5842E283C836D600755786397|YfiR]: repression, [pubmed|], in [regulon|15DE8BAFB36296B5842E283C836D600755786397|YfiR regulon]view in new tabgenes
[gene|15DE8BAFB36296B5842E283C836D600755786397|yfiR]
description
[Pubmed|22383849]
view in new tabBiological materials
Mutant
MGNA-C356 (yfiR::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2354 NBRP B. subtilis, Japan]BKE08370 ([gene|15DE8BAFB36296B5842E283C836D600755786397|yfiR]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE08370 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GTTTATCCTTGTGCTCCTTT, downstream forward: _UP4_TAAAGAAACGCGGCAGGAGCBKK08370 ([gene|15DE8BAFB36296B5842E283C836D600755786397|yfiR]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK08370 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GTTTATCCTTGTGCTCCTTT, downstream forward: _UP4_TAAAGAAACGCGGCAGGAGCReferences
Reviews
Original publications
25755103,16862575,22383849